Triple negative breast cancer originating from a cystic lesion

Authors

DOI:

https://doi.org/10.29289/2594539420220013

Keywords:

breast neoplasms, fibrocystic breast disease, pregnancy, triple negative breast neoplasms

Abstract

ABSTRACT: Malignant neoplasm diagnosed after radiological evaluation of a simple breast cyst is rare. This report described the case of a young patient with an initial simple cystic lesion, whom, in 18-month follow-up examinations, showed a change in the imaging pattern of the cyst, and underwent biopsy, where a triple negative carcinoma was identified. In addition, the diagnosis occurred during pregnancy, which makes the present report even rarer. 

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References

Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209-49. https://doi.org/10.3322/caac.21660

Howard FM, Olopade OI. Epidemiology of Triple-Negative Breast Cancer: A Review. Cancer J. 2021;27(1):8-16. https://doi.org/10.1097/PPO.0000000000000500

Trivers KF, Lund MJ, Porter PL, Liff JM, Flagg EW, Coates RJ, et al. The epidemiology of triple-negative breast cancer, including race. Cancer Causes Control. 2009;20(7):1071-82. https://doi.org/10.1007/s10552-009-9331-1

Tagliafico AS, Piana M, Schenone D, Lai R, Massone AM, Houssami N. Overview of radiomics in breast cancer diagnosis and prognostication. Breast. 2020;49:74-80. https://doi.org/10.1016/j.breast.2019.10.018

European Society of Radiology (ESR). Medical imaging in personalised medicine: a white paper of the research committee of the European Society of Radiology (ESR). Insights Imaging. 2015;6(2):141-55. https://doi.org/10.1007/s13244-015-0394-0

Mehta N, Rousslang L, Shokouh-Amiri M, Wiley EL, Green L. Complex Solid and Cystic Breast Cancer: A Series of Six Case Reports. J Radiol Case Rep. 2020;14(2):21-44. https://doi.org/10.3941/jrcr.v14i2.3712

Athanasiou A, Aubert E, Vincent Salomon A, Tardivon A. Complex cystic breast masses in ultrasound examination. Diagn Interv Imaging. 2014;95(2):169-79. https://doi.org/10.1016/j.diii.2013.12.008

Doshi DJ, March DE, Crisi GM, Coughlin BF. Complex cystic breast masses: diagnostic approach and imaging-pathologic correlation. Radiographics. 2007;27(Suppl 1):S53-64. https://doi.org/10.1148/rg.27si075508

Foulkes WD, Smith IE, Reis-Filho JS. Triple-negative breast cancer. N Engl J Med. 2010;363(20):1938-48. https://doi.org/10.1056/NEJMra1001389

Jaffer S, Chen X, Lee L, Bleiweiss IJ. Pleomorphic solid and cystic papillary carcinoma of the breast: two cases occurring in young women. Ann Diagn Pathol. 2004 Jun;8(3):126-9. https://doi.org/10.1016/j.anndiagpath.2004.03.003

Shin SJ, Rosen PP. Carcinoma arising from preexisting pregnancy-like and cystic hypersecretory hyperplasia lesions of the breast: a clinicopathologic study of 9 patients. Am J Surg Pathol. 2004;28(6):789-93. https://doi.org/10.1097/01.pas.0000126060.20455.27

Sabate JM, Clotet M, Torrubia S, Gomez A, Guerrero R, de las Heras P, et al. Radiologic evaluation of breast disorders related to pregnancy and lactation. Radiographics. 2007 Oct;27 Suppl 1:S101-24. https://doi.org/10.1148/rg.27si075505

13. Iqbal J, Amir E, Rochon PA, Giannakeas V, Sun P, Narod SA. Association of the timing of pregnancy with survival in women with breast cancer. JAMA Oncol. 2017;3(5):659-65. https://doi.org/10.1001/jamaoncol.2017.0248

14. Burstein HJ, Curigliano G, Thürlimann B, Weber WP, Poortmans P, Regan MM, et al. Customizing local and systemic therapies for women with early breast cancer: the St. Gallen International Consensus Guidelines for treatment of early breast cancer 2021. Ann Oncol. 2021;32(10):1216-35. https://doi.org/10.1016/j.annonc.2021.06.023

15. Breast Cancer Association Consortium, Dorling L, Carvalho S, Allen J, González-Neira A, Luccarini C, et al. Breast Cancer Risk Genes – association analysis in more than 113,000 women. N Engl J Med. 2021;384(5):428-39. https://doi.org/10.1056/NEJMoa1913948

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Published

2026-04-17

How to Cite

Moreno, M., Franciosi, M. L. M., & Araújo, J. B. de. (2026). Triple negative breast cancer originating from a cystic lesion. Mastology, 32. https://doi.org/10.29289/2594539420220013

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Section

Case Reports