Breast cancer during pregnancy: a case series
DOI:
https://doi.org/10.29289/2594539420250036%20Palavras-chave:
breast neoplasms, pregnancy, breast feeding, drug therapy, patient care team, treatment outcomeResumo
This study analyzed seven cases of breast cancer diagnosed during pregnancy or within one year of breastfeeding at a private clinic in Teresina (PI), Brazil, between 2012 and 2024. The mean patient age was 33.1 years, with a mean gestational age at diagnosis of 24 weeks. Triple-negative subtype tumors predominated, followed by luminal hybrid and luminal B. Only one patient carried a pathogenic mutation (MUTYH); no BRCA1/2 mutations were identified. Most patients received neoadjuvant chemotherapy with anthracyclines, cyclophosphamide, and taxanes; immunotherapy was used in only one recent case. Surgery was performed in all patients, with a breast-conserving approach in only one. Radiotherapy was indicated for six patients, including axillary treatment in three. No fetal malformations attributable to chemotherapy were observed. Multidisciplinary management allowed all deliveries to occur after fetal maturation, without relevant neonatal complications. One patient with initially metastatic disease achieved complete remission after multimodal treatment and remains without evidence of active disease. Mean overall survival was 85.7 months, with a mean follow-up of 52 months.
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Copyright (c) 2026 Samuel de Castro Campos, Sabas Carlos Vieira
Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.
