DY OF THE TECHNIQUES FOR THE SENTINEL LIMPH NODE IN BREAST CÂNCER
Keywords:
Breast, Carcinoma, Sentinel limph node, CintilographAbstract
lary lymphadenectomy for the treatment of breast carcinoma can benefit the
patient only if there is lymph nodes metastasis. Methods used to evaluate lymph node
status were inefficient in he majority of cases invasive carcinoma. The search for the sentinel
lymph node has presented a high negative predictive value (NPV). Aknowledge of its use
and limitations is important. Objective: The analisis of various techniques to search for
sentinel lymph node (SLN). Method: 81 cases of breast carcinoma were studied with
clinicaly negative axilla. Of these, the dyeing technique was used in 36 cases, the probe
tecnique was used in 6 cases and 39 both tecniques were used simultaneously. A total
axillary dissection was done in every case, except for two. Results: The SLN was found in
74 cases and of these, 35 with axillary metastases. There were two false-negative results. Of
the 36 cases where the dyeing tecnique was used, the SLN was found in 32 cases and of
these, 21 presented axillary metastases and there were one false-negative results. The SLN
was found in ali 6 cases using the probe tecnique, two had axillary metastases and there
were no false-negative results. The SLN was found in 36 of the 39 cases using the two
different tecniques. In 34 cases it was found by the two methods and there were one falsenegative. In the other 2 cases there was a disagreement between the two methods and of
these, two were false-negative (these two cases are contained in the first six using the
probe). Conclusion: The predictive negative value of the SLN is very hight in the different
tecniques and will be used as a method to avoid axillary dissection in certain cases.
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References
1.BARTH A, CRAIG PH, SILVERSTEIN MJ.
Predictors of axillary lymph node metastases in
patientes with TI breast carcionoma. Câncer 1997;
79: 1918-22.
2.BORGSTEIN PJ, PIJPERS R, COMANS EF,
DIEST PJ. BOOM RP. MEIJER S. Sentinel lymph
node biopsy in breast câncer: guidelines and pitfalls
of lymplhoscintigraphy an gamma-probe detection.
J Am Coll Surg 1998; 186: 275-83.
3.CÂNCER RESEARCH CAMPAIGN (KING'S/
CAMBRIDGE) TRIAL FOR EARLY BREAST
CÂNCER. Câncer Reseach Campaing Working
Party. Lancet 1980; 12: 55-60.
4.CHADHA M. CHABON AB, FRIEDMANN P,
VIKRAM B. Predictors of axilary lymph node
metastases in patients with TI breast câncer.
Câncer 1994; 73: 350-3.
5.CODYIIIHS. Sentinel lymph node biopsy. In: The
new national comprehensive câncer network
guidelines diseases: a yearbook quarterly. 1998; 9:
228-9.
6.COX CE, PENDAS S, COX JM et al. Guidelines
for sentinel node biopy and lymphatic mapping of
patients whit breast câncer. Ann Surg 1998; 227:
645-53.
7.FISHER B. REDMOND C, FISHER ER et al. Tenyear results of randomized clinicai trial comparing
radical mastectmy and total mastectomy with or
without radiation. New Engl J Med 1985; 312:
674-81.
8.FLETT MM. GOING JJ, STANTON PD, COOKE
TG. Sentinel node localization in patients with
breast câncer. Brit J Med 1998; 85: 991-3.
9.GALEB NA. Valor da embolização linfática
peritumoral como elemento preditivo de comprometimento metastático axilar no câncer mamário.
VIII Congresso Brasileiro de Mastologia. Belo
Horizonte, 1992.
10.GIULIANO AE. Mapping a pathway for axillary
staging - a personal perspective on the currents
status of sentinel lymph node dissection for breast
câncer. Arch Surg 1999; 134: 195-9.
11.HARRIS JR, OSTEEN RT. Patients with early breast
câncer benefit from effective axilliary treatment. Breast
Câncer Res Treat 1985; 5: 17-21.
12.KRAG DN. Minimal acces surgery for staging
regional lymph nodes: the sentinel node concept.
Curr Prob In Surg 1998; 35: 953-1015.
13.KRAG D. WEAVER D, ASHIKAGA T et al. The
sentinel node in breast câncer. New Eng J Med
1998; 339: 941-6.
14.LOZA DJB, COLO F, SPORN V, MARTÍNEZ FS,
GALICH M, CHACON R. Biopsia dei gânglio
centinela - Una técnica para evitar la linfadenectomia
axilar en pacientes com câncer de mama axila
negativa. Focus 1997; 19-23.
15.LYTHGOE JP. PALMER MK. Manchester regional breast study - 5 and 10 year results. Br J Surg
1982; 69: 693-6.
16.NWARIAKU FE, EUHUS DM, BEITSCH PD et al.
GN. Sentinel lymph node biopy, an alternative to
elective axillary dissection for breast câncer. Am J
Surg 1998; 176: 529-31.
17.0'HEA BJ. HILL ADK, EL-SHIRBINY AM et al.
Sentinel lymph node biopsy in breast câncer: initial
experience at memorial slon-kettering câncer. J Am
Coll Surg 1998; 186: 423-7.
18.OLLILA DW, GIULIANO AE. Intraoperative
lymphatic mapping and sentinel lymphadenectomy
using isosulfan blue dye. In: Breast diseases: a year
book quarterly. 1998; 8: 297-301.
19.VERONESI U, VALAGUSSA P. Inefficacy of
internai, mammary nodes dissection in Breast
câncer surgery. Câncer 1981; 47: 170-5.
20.VERONESI U, PAGANELLI G, VIALE G et al.
Sentinel lymph node biopsy and axillary dissection in
breast câncer: results in a large serie. J Natl Câncer
Inst 1999; 91: 368-73.
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Copyright (c) 2026 Nassif Alexandre Galeb Jr., Márcia Modesto Garrido, Laurival Antonio De Luca, Cyntia Ap. B. Toledo Osório, Ronaldo L. Rangel Costa, Pedro Luiz Gamaeiro, João Carlos Sampaio Góes

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