Pseudoangiomatous stromal hyperplasia clinical patological study of two cases
Keywords:
Pseudoangiomatous stromal hyperplasia, Breast, Nodular tumorAbstract
The pseudoangiomatous stromal hyperplasia (PASH) ofthe breast is a common microscopic lesion that
may befound incidentally at breast biopsies, and presents histologically with a proliferation ofthe stromal
cells and slit-like pseudovascularspaces with endothelial-like spindle cells. Macroscopically, this lesion presents as a palefibroblastic mass, well-circunscribed and, less commonly, may be seen as a palpable nodule.
Most PASH lesions grow slowly and may regress spontaneously. The treatment usually consists of wide
local excision. PASH has a benign origin, good prognosis and there have been no cases of PASH becoming
malignant. We report here two cases of PASH with distinct presentations. It is important to distinguish
PASH from other breast tumors like fibroadenoma, phillodes tumor, hamartoma and angiosarcoта.
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Copyright (c) 2026 Ana Paula Martins Sebastião, Cléverton César Spautz, Cícero de Andrade Urban, Fátima Satomi Nishimori, Gustavo Rocha Dissenha, Francielle Melina Nihi
This work is licensed under a Creative Commons Attribution 4.0 International License.
