UM NOVO MARCADOR DE ATIVIDADE PROLIFERATIVA (PCNA/CICLINA)
Palavras-chave:
Câncer de mama, Fatores prognósticos, PCNAResumo
Os autores relatam a importância dos fatores prognósticos no tratamento do câncer de
mama. Observam que os dados clínicos e os parâmetros anátomo-patológicos são insuficientes
para estimar o prognóstico, particularmente quando os linfonodos axilares apresentam-se
livres de comprometimento neoplásico. Evidenciam que nos recentes anos as pesquisas buscam
espelhar a agressividade tumoral através das informações da fração de crescimento tumoral e
das células em proliferação. Fazem uma revisão dos marcadores de atividade proliferativa e
apresentam um novo polipeptídeo, identificável em material parafinado, facilmente adaptável
à rotina laboratorial e que apresenta resultados altamente significativos quando correlacionados
com os fatores prognósticos.
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Referências
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Copyright (c) 2026 Claudio Kemp, Geraldo Rodrigues de Lima, Vania Alberti, Filomena Marina Carvalho
Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.
