28592 – FACTORS ASSOCIATED WITH SURVIVAL IN PATIENTS WITH TRIPLE-NEGATIVE BREAST CANCER

Abstract

Introduction: Triple-negative breast cancer (TNBC) accounts for 15%–20% of breast cancer cases. The most affected
population includes young women and women of African descent, who tend to have a poorer prognosis and survival due
to the tumor’s aggressiveness. Given the lack of molecular targets in this group, the standard treatment remains cytotoxic chemotherapy. However, immunotherapy has shown benefits in larger tumors and cases with positive axillary lymph
nodes. Methodology: An observational, retrospective, and descriptive study was conducted, analyzing data from medical
records of patients diagnosed with triple-negative breast cancer between 2008 and 2023 at a private oncology clinic located in the city of Teresina (PI). This study is part of a research project on cancer patients approved by the Research Ethics
Committee of the State University of Piauí (CEP-UESPI); approval number: 4.311.835. Conclusion: In the present study, the
main factors associated with prognosis were the presence of metastasis, axillary involvement, recurrence, and mutations.