Ductal carcinoma in situ in men presenting gynecomastia: case report and literature review
Keywords:
Breast carcinoma, in situ, MenAbstract
Ductal carcinoma in situ, an extreme/y rare occurrence in maie patients, accounts for
approximateiy 7% of aii breast carcinomas. In contrast, in women ductai carcinoma in situ
occurs in 20% to 25% of aii cases of femaie breast câncer. Compareci to invasive breast
carcinoma, the prognosis associated with carcinoma in situ in men is reiativeiy favorabie, in
spite of variations in clinicai presentation. The authors report a case of histopathologically
confirmed ductal carcinoma ductal in situ, with early signs of infiltration, associated with
gynecomastia in an otherwise healthy 48-year-o/d patient submitted to a left-sided
adenomastectomy. The patient was subsequentiy submitted to mastectomy and
lymphadenectomy of the axilla. An anatomic pathology examination followed by an
immunohistochemicalpane! revea/ed gynecomastia associated with micropapillary ductai carcinomam situ without involvement of the axilla.
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Copyright (c) 2026 Paulo Roberto de Souza Coelho, Elisvania Rodrigues da Silva, Francisco valdeci de Almeida Ferreira, Sérgio Ferreira Juaçaba
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